1. Clean and dry the target area. 2. Remove the patch from the protective sheet, and apply it on the target area. 3. Press down for 15-30 seconds to ensure the micro needles penetrate the skin and the outer edge is 4. properly adhered. 5. Wear for at least 2 hours. For better result, for best results apply the patch overnight before bedtime. 6. Peel off and moisturize area.